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Study: APOE4 Homozygosity 'Almost Guaranteed' to Cause Alzheimer's

  • #Diseases & conditions
  • #Research
  • #Medicine & healthcare
  • #Genetics & heredity
Study: APOE4 Homozygosity 'Almost Guaranteed' to Cause Alzheimer's
story
MAY 2024
Image copyright: Mikael Häggström, M.D. via Wikimedia Commons
story last updated MAY 2024

The Spin

Narrative A

While frightening on the surface, this news is a boon to Alzheimer's researchers' efforts to find a cure. The identification of APOE4 as a singular cause of the disease in some individuals will unlock new treatments and spur research toward some of the most serious manifestations of the disease, such as early-onset Alzheimer's.

Bloomberg

Narrative B

While this is promising research, we can't rely on genetics to solve the disease. Researchers are strongly warning people against APOE4 testing, as the fatalism could cause despair in patients. The scientific community should focus on proven, non-invasive lifestyle treatments, including diet and exercise.

Los Angeles times

Metaculus Prediction


Articles on this story

Study Suggests Genetics as a Cause, Not Just a Risk, for Some Alzheimer’s
New York TimesMAY 2024
Alzheimer's Breakthrough as 'Protective' Gene May Open Up New Treatments
NewsweekAPR 2024
Gene mutation that ‘reduces odds of Alzheimer’s disease by 70%’ discovered
IndependentAPR 2024
Genes known to increase the risk of Alzheimer’s may actually be an inherited form of the disorder, researchers say
CNNMAY 2024